Seminar 2006 12 13 Lung Cancer Ablation
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CISST ERC Seminar
Lung Cancer Ablation
Date: Wednesday, December 13, 2006
Time: 12:00pm
Place: Maryland 110 (Lunch will be served)
Speaker: Filip Banovac
Title: New Frontiers in Treatment of Lung Cancer - Image Guided Radiofrequency Ablation
Presentation: PDF, not yet uploaded
Abstract
Lung cancer is a leading cause of cancer deaths among men and women in the United States in 2005.
In women, lung cancer deaths have been on a steady rise since 1960's, surpassing breast cancer in mid 1980's. Surgical resection remains the only accepted modality with curative potential for early non-small cell lung cancer (NSCLC) although 5-year survival is marginal even after surgical treatment of early disease. Moreover, only about a third of patients are candidates for resection because of concomitant pulmonary disease. Although chemo-radiation offers a modest improvement in survival, the gain comes with substantial toxicity.
Starting in the late 1990's, investigators started to employ minimally invasive percutaneous techniques to treat lung cancer and lung metastases.
Percutaneous thermal ablation has gained increasing acceptance in treatment of solid neoplasm in multiple organ systems including liver, kidney, and bone. Lately, RFA for treatment of lung tumors has gained momentum and several clinical studies have been performed. The guiding principle for thermal ablation of the lung is the same as in other organ systems: thermal coagulation of the tissue with cell death. The procedure has been established to have an acceptable safety profile. Pneumothorax is by far the most common complication and it requires treatment in about 1/3 of the patients. An international survey of major centers performing RFA of the lung, reports negligible mortality and acceptable morbidity.
Bio
Dr. Filip Banovac is an Assistant Professor of Radiology in the Division of Interventional Radiology at Georgetown University Hospital, Washington, DC. A former National Institutes of Health research fellow, he is now the clinical director of the Imaging Sciences and Information Systems Center (ISIS) at Georgetown Medical Center. He after his residency in Radiology at Georgetown he did his clinical fellowship in Vascular and Interventional Radiology at Stanford University. He now leads a group of researchers at Georgetown Medical Center in the field of image guided oncologic treatments. Dr. Banovac His latest research is in computer assisted instrument guidance for ablative therapies of inoperable lung cancer.