Seminar 2007 04 03 Photonic Imaging

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The Johns Hopkins University
Whiting School of Engineering
Department of Electrical and Computer Engineering

Photonic Imaging Technologies and Potential Clinical Applications

Date: Tuesday, April 3, 2007
Time: 11:00am
Place: Barton 320A

Speaker: Xingde Li
University of Washington
Title: Photonic Imaging Technologies and Potential Clinical Applications

Abstract

Non-invasive biophotonic imaging technologies, such as optical coherence tomography (OCT), two photo fluorescence (TPF) and second harmonic generation (SHG) imaging, are emerging as a new modality with a great translational potential for clinical applications, including detection of diseases at early stages, guidance of surgical interventions and monitoring of t6herapeutic effects without the need for tissue removal. The technologies are drawn upon fiber-optics, offering and extremely compact footprint and providing structural, functional, and potentially molecular or biochemical information of biological tissues at micron-scale resolution and in real time. In this seminar, we will present some exemplary applications of biophotonic imaging technologies for (1) detection of diseases that are very challenging with current clinically available technologies, and (2) for assessing normal and stimulated wound healing processes. We will also report on recent advances in developing ultra small fiber-optic Endomicroscopes that are instrumental for in vivo and clinical of OCT, TPF and SHG imaging technologies. Furthermore, development of molecular target agents based on structured nanoparticles that can be used in conjunction with biophotonic imaging will also be discussed

Note

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